​© 2023 by Angry Man Pictures
Alex Tweddle Producer & Director
AMR - DYING TO CHANGE THE WORLD
AMR - DYING TO CHANGE THE WORLD
AMR – Dying to Change the World’ thrusts viewers into the heart of a looming catastrophe: Antimicrobial Resistance (AMR), the silent threat poised to shatter the foundations of global health, food systems, the environment and economic stability as we know it. This is not just a medical issue—this is an existential crisis. The World Health Organization warns that AMR, the insidious rise of drug-resistant superbugs, now stands shoulder-to-shoulder with the most terrifying dangers facing humanity, threatening to drag us back into a pre-antibiotic era where even minor infections could prove deadly.
The film unflinchingly exposes the root causes, devastating impact and the urgent, radical measures needed to stop AMR’s relentless advance—before we stumble into a new global pandemic, one far worse than Covid-19. This is the warning siren no leader can afford to ignore; action delayed today could mean millions of lives lost tomorrow
A unique approach to narrating this compelling story
What makes this story unforgettable is the chilling narrative device: we witness the unfolding horror through the eyes of AMR itself, given voice by the legendary Brian Cox (Succession). AMR breaks the fourth wall, speaking directly to us in a manner both intimate and unsettling, before taking on a godlike drone’s-eye view, revelling in its own evolution and unrestrained journey across the globe. It then confronts those on the front lines—scientists, doctors, and innovators—fighting desperately to slow its onslaught. The film’s climax is nothing short of haunting: AMR gazes into the camera, daring us to imagine a world in 2050 where medicine has failed, and our greatest enemy is one we created ourselves.
Themes
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The film sends an important message, that science must constantly evolve and be innovative in order to transform human lives.
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It illustrates how power, greed and political unwillingness can hinder scientific advancement. This is even more evident now in the aftermath of the Covid-19 global pandemic.
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The film also raises important questions about the ethics of intensive animal farming. Does the end justify the means in combatting a global threat or grand pandemic/recession?
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The film questions why international legislation on food production and pharmaceutical distribution of substandard drugs is not being adhered to.
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It reconfigures all the key elements that constitute a traditional documentary to engage as wide an audience as possible.
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​Recent Reviews
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Tweddle transforms a complex medical issue into a compelling human story
https://takeonecinema.net/2025/alex-tweddle-amr-dying-to-change-the-world
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AMR - Dying to Change the World: Thoughts and reflections
https://www.digitalamr.org/blog/film-screening-amr?
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Brian Cox at his chilling best!
https://www.linkedin.com/posts/david~powell_amr-activity-7305508900454232064-scSv/
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Brian Cox has played some complex and terrifying roles
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AMR – Dying to Change the World: London Pre-screening review
https://amrnarrative.org/fleming-initiative-movie-premier/
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Fleming Initiative hosts special advanced screening of 'AMR - Dying to Change the World'
https://www.fleminginitiative.org/post/screening
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A new film lays bare the existential threat driven by antibiotic overuse - and comes after years of warning
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